BDBM50305818 1-(biphenyl-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione::CHEMBL593506::cid_45281794
SMILES FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
InChI Key InChIKey=SPBGRXOPAXZSER-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50305818
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: >442nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Muscarinic acetylcholine receptors are family A GPCRs comprised of...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 1.60E+3nMAssay Description:Positive allosteric modulation of muscarinic M5 receptor expressed in CHO cells assessed as effect on acetylcholine-induced intracellular calcium mob...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 2.70E+3nMAssay Description:Agonist activity at human muscarinic M5 expressed in CHO cells assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair